Reduction of body weight, food intake, and visceral fat size in high fat diet-induced obese mice and ob/ob mice by PPB from E. cava (A) Body weight, body composition (fat mass and lean mass), and (B) food intake of high fat diet–induced obese mice were measured before sacrifice. (C) Visceral fat was stained with hematoxylin and eosin (H&E). (D) Body weight, body composition (fat mass and lean mass), and (E) food intake of ob/ob mice were measured before sacrifice. (F) Visceral fat was stained with H&E. The size of the cells was quantified using Image J software and is shown as a graph. Scale bar = 50 µm. Significance represented as ***, p < 0.001 versus NFD-Saline or WT-Saline; $$$, p < 0.001 versus HFD-Saline or ob/ob-Saline; ##, p < 0.01 versus ob/ob-PPB. PPB, pyrogallol-phloroglucinol-6,6-bieckol.