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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Target Oncol. 2019 Oct;14(5):563–575. doi: 10.1007/s11523-019-00662-4

Figure 4.

Figure 4.

The effect of AURKA inhibition and/or cyclophosphamide on cell cycle and apoptosis in chemosensitive (Ramos) and chemoresistant (Raji) Myc-positive cell lines. (a) DNA profiles of Ramos or Raji cells treated with PBS control, cyclophosphamide, MLN8237, or combination of cyclophosphamide and MLN8237. (b) Induction of apoptosis measured by flow cytometry with Annexin V FITC in Ramos or Raji cells treated with PBS control, cyclophosphamide, MLN8237, or combination of cyclophosphamide and MLN8237.