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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Target Oncol. 2019 Oct;14(5):563–575. doi: 10.1007/s11523-019-00662-4

Figure 8.

Figure 8.

Tumor response and survival of mice bearing lymphoma xenografts. Tumor growth of (a) chemosensitive (Ramos) and (b) chemoresistant (Raji) xenografts in athymic treated with saline (negative control, ◻), cyclophosphamide (∎), MLN8237 (Δ), or combination of cyclophosphamide and MLN8237 (●). The data points represent mean values with the standard error of the mean (SEM) curves. The tumor response assessment was performed using the paired t test. P value of < 0.05 was deemed statistically significant. Survival of mice bearing (c) chemosensitive (Ramos) and (d) chemoresistant (Raji) xenografts treated with saline (negative control, ◻), cyclophosphamide (∎), MLN8237 (Δ), or combination of cyclophosphamide and MLN8237 (●). The survival time was estimated using the method of Kaplan-Meier.