Table 2.
Group Assignment
| Animal | Treatment | 5A Peptide a | Fx-5A |
|---|---|---|---|
| Numbers (Sex) | Dose Level (mg/kg) | Dose Volumed (mL/kg)c | |
| 101 to 103 (Males) | Control | 0 | 5.0b |
| Low Dose | 8 | 0.5 | |
| 151 to 155 (Females) | Mid Dose | 25 | 1.7 |
| High Dose | 75 | 5.0 | |
a
dose is expressed in 5A peptide equivalent.
b
Volume of vehicule (20mM sodium phosphate, pH 5.1) injected
c
The actual dose volume (mL/kg) administered to each monkey was based on that animal’s most recent body weight.
d
[peptide 5A (15 mg/mL) with egg sphingomyelin (ESM) (21.50 mg/mL)].