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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: IUBMB Life. 2019 Jul 8;71(8):1158–1166. doi: 10.1002/iub.2120

FIG 4.

FIG 4

Synthesis of xm5U modifications. R represents the 5′-phosphoribosyl group of the tRNA backbone. Installation of s2U is a multi-step sulfur trafficking pathway. Figure adapted from Armengod et al., Biochimie, 94, 1510–1520 (33).