Skip to main content
. Author manuscript; available in PMC: 2019 Dec 5.
Published in final edited form as: Cell Tissue Res. 2018 Mar 27;372(2):287–307. doi: 10.1007/s00441-018-2820-3

Fig 1. Annotated map of ALK kinase domain and kinase domain crystal structure.

Fig 1

Mutations identified in hereditary neuroblastoma families are shown. Slate blue, NT lobe, residues 1093-1199. Grey, CT lobe, residues 1200-1399. Cyan, P-loop, residues 1123-1128. Purple, αC-helix, residues 1157-1173. Red, catalytic loop, residues 1247-1254. Orange, A-loop, residues 1270-1299. NT, N-terminus. CT, C-terminus. Crystal structure figure produced via PyMOL software (Lee et al. 2010; Chand et al. 2013; Bresler et al. 2014).