Table 3.
MIC of MDR Escherichia coli isolates in the absence and presence of omeprazole.a
| Antibiotics | MIC of antibiotics against E. coli isolates |
MIC reduced in the presence of omeprazole (fold) | MIC of antibiotics against E. coli ATCC 25922 (µg/µL) | |
|---|---|---|---|---|
| in the absence of omeprazole (µg/µL) | in the presence of omeprazole (µg/µL) | |||
| AMX | 4-8 | 2-4 | 2 | 0.5 |
| AZM | 4-8 | 1-2 | 4 | 0.5 |
| CFM | 2-4 | 0.25-0.5 | 8 | 0.125 |
| CIP | 4-8 | 0.5-1 | 8 | 0.5 |
| CTR | 2-4 | 0.5-1 | 4 | 0.5 |
| GEN | 1-2 | 0.125-0.25 | 8 | 0.0625 |
| SXT | 4-8 | 2-4 | 2 | 2 |
Abbreviations: AMX, amoxicillin; AZM, azithromycin; CFM, cefixime; CIP, ciprofloxacin; CTR, ceftriaxone; GEN, gentamicin; MIC, minimum inhibitory concentration; MDR, multidrug resistant; SXT, sulfamethoxazole.
a
Every experiment was repeated at least 3 times.