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. 2019 Nov 19;34(11):2297–2310. doi: 10.1093/humrep/dez134

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© The Author(s) 2019. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Upregulation of X-linked genes in ips-KS2 related to nervous system development, synaptic transmission, and metabolic processes. (A) Chromosomal distribution of upregulated DEGs comparing either ips-KS1 or ips-KS2 with HM hiPSCs. See also Supplementary Table SIX. (B) Expression of X-linked genes showing up-regulated expression in ips-KS2 compared to HM hiPSC. Mean expression of three biological replicates with ±SD. Asterisk indicates upregulated genes that showed also bi-allelic expression in ips-KS2. See also Supplementary Tables SVIII and SIX.