Supplement Table 3.
Mean values comparing the clinical parameters of patients with valvular heart disease in different groups of β-catenin expression in the myocardium.
| Indices | Weak | Strong | Very strong | P |
|---|---|---|---|---|
| EF (%) | 63.1667±8.537 | 60.429±7.138 | 63.900±7.219 | 0.618 |
| LA (mm) | 58.000±25.856 | 45.857±10.961 | 61.400±17.702 | 0.300 |
| LVD (mm) | 54.000±9.737 | 50.429±11.886 | 50.700±8.564 | 0.583 |
| LVS (mm) | 35.083±6.037 | 33.714±8.180 | 32.600±4.835 | 0.213 |
| IVS (mm) | 10.333±2.146 | 10.428±1.989 | 8.850±1.292 | 0.131 |
| LVPW (mm) | 9.917±1.564 | 9.857±1.574 | 9.200±1.398 | 0.508 |
| RA (mm) | 57.000±16.321 | 53.571±14.397 | 61.700±8.932 | 0.479 |
| RV (mm) | 23.000±3.693 | 32.429±18.293 | 23.400±2.119 | 0.087 |
| Fibrosis degree | 0.160±0.109 | 0.139±0.066 | 0.164±0.053 | 0.817 |
As long as the sample contained cells with β-catenin cytoplasmic and/or membrane staining, the total expression level was regarded as negative if mean density was <0.01, positive if it was between ≥0.01 and <0.013, and strongly positive if it was ≥0.013. Fibrosis degree was detected by Masson's staining. Fibrosis degree=the area of fibrosis/total area. P-value comparison was performed between the three groups with analysis of variance.
EF=ejection fraction; IVS=interventricular septum; LA=left atrial; LVD=left ventricular diastolic; LVPW=left ventricular posterior wall; LVS=left ventricular systolic; RA=right atrial; RV=right ventricular