Figure 3.
CDC administration attenuates injury following pneumonia. A, B) PV mechanics: Closed-chest PV mechanics were measured at 24 h (A) and 48 h (B) after KP (n = 6/group). C) Permeability injury: Albumin concentration in the BAL was determined by ELISA (n = 16). D, E) Pathologic injury: Representative hematoxylin and eosin lung sections at 24 and 48 h following KP and CDC administration (n = 3/group) are shown at ×400 original magnification (D), and the degree of pathologic injury was calculated (E). Statistical analysis was performed at each time point with a 2-tailed, unpaired Student’s t test with Welch’s correction. *P < 0.05 CDC vs. KP; #P < 0.05 KP vs. KP + CDC.