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. 2019 Oct 26;33(12):14147–14158. doi: 10.1096/fj.201900786R

Figure 2.

Figure 2

EC-specific Glrx overexpression impaired ischemic angiogenesis in mice. A) Blood flow after hind limb ischemia surgery, assessed by Laser Doppler. Representative photos show the blood flow recovery. B) EC-Glrx TG mice were compared with VEcad-tTA (single TG) or wild-type mice as control with quantitative serial assessment, n = 8 each. C) Representative photos show necrotic foot observed with EC-Glrx TG mice. D) Limb survival curve indicates that EC-Glrx TG mice had a higher incidence of necrotic legs. *P < 0.05.