TABLE 3.

Western blot analysis of P-gp and hmPGES-1 protein expression levels in isolated brain capillaries exposed to glutamate and BI1029539

Exposure	P-gp	hmPGES-1
Control	100 ± 7.0	100 ± 1.9
100 µM glutamate	166 ± 10.9*	132.8 ± 3.5*
+1 µM BI1029539	91.8 ± 6.7	91.5 ± 2.3*
1 µM BI1029539	91.0 ± 5.2	91.8 ± 1.7*

Data were normalized to β-actin levels; values are given as the percentage of control ± sem (n = 3). See Fig. 5C.

^*P < 0.01 for each endpoint compared with control (Dunnett’s many-to-one t test).