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. 2019 Dec 4;16:253. doi: 10.1186/s12974-019-1629-7

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Cytokine variation and outcomes by human immunomonitoring. Group-wise mean levels and distribution of selected cytokines at D0, D1, D2, D5, and D10 stratified by outcomes, 7 patient had good outcomes (good outcome defined as an mRS of 0–3 at 1 year), 3 patients had worse outcomes and 3 patients had unknown outcomes, with baseline levels in healthy controls (line parallel to the x axis). Our observations support a different longitudinal evolution among patients with favorable outcomes compared with those with a worse outcome based on ICAM-1, bFGF, IL-7, IL-12p40, and MCP-4