Fig. 1.

Relative miR-582–3p expression at the mRNA level in blood samples from leukemia patients and leukemia cell lines. a The expression of miR-582–3p was determined in fresh blood samples from patients with acute myeloid leukemia (AML; n = 20), T-cell acute lymphoblastic leukemia (T-cell ALL; n = 20) and chronic myeloid leukemia (CML; n = 20) using quantitative real-time PCR with U6 as the internal control. b The expression of miR-582–3p was determined in 3 leukemia cell lines (THP-1, Molt-4 and K562) and in normal HS-5 cells using quantitative real-time PCR with U6 as the internal control. ***p < 0.001 vs. controls; ^##p < 0.01, ^###p < 0.001 vs. HS-5 cells