Table 5.

Univariate analysis of Relapse Free Survival in ER+ patients

Variable	Events / At risk	% Survival	P	HR	95% CI
Fasting / Carbohydrate
Fasting	1/29	97
Carbohydrate	6/21	71	0.012	9.34	1.12 –77.7
S-Pyruvatea
< 12.5	2/39	95
≥ 12.5	5/10	50	<0.0001	13.59	2.61– 70.6
S-Lactatea
< 56.9	3/40	93
≥ 56.9	4/9	56	0.002	7.47	1.66 – 33.6
S-Preoperative Insulin
< 18.3 I.U.	1/29	97
≥ 18.3 I.U.	6/21	71	0.012	9.34	1.12 – 77.7
S-Preoperative C-peptide
< 1.22 nM	1/29	97
≥1.22 nM	6/21	71	0.011	9.51	1.14-79.0
Tumor Glutathione
< 1.09	0/10	100
≥ 1.09	3/8	63	0.038	Inf.
Tumor size
T1	3/40	93
T2	4/10	60	0.003	7.09	1.57-31.9
Nodal status
N0	3/33	91
N+	4/17	73	0.160	2.80	0.625-12.6
Grade
1	0/11	100
2+3	7/39	82	0.136	31.1	0.019 – 50547
MAIa
<10	4/39	90
≥10	3/10	70	0.092	3.38	0.751–15.2
Ki67a
<30%	3/37	92
≥30%	4/12	67	0.023	4.84	1.08 – 21.8
PPH3
<13	3/35	91
≥13	4/15	73	0.116	3.13	0.699-14.0

^aMissing information on one patient in the ER+ group leading to n=49 patients analyzed for this variable