Table 1.
Effects of upper-airway surgery on components of MetS in patients with OSA with and without EDS
| OSA without EDS (n = 24) | OSA with EDS (n = 33) | Differences in after-before upper-airway surgery between patients with and without EDS (95%CI) | p value | |||
|---|---|---|---|---|---|---|
| Before upper-airway surgery | After upper-airway surgery | Before upper-airway surgery | After upper-airway surgery | |||
| Glucose(mmol/L) | 5.43(0.72) | 5.00(1.48) | 5.28(0.69) | 5.03(1.14) | −0.28(− 0.76~0.21) | 0.61 |
| Insulin(μU/mL) | 10.50(4.95) | 10.65(4.83) | 15.83(11.05) | 15.66(8.00) | −1.81(−4.51~0.89) | 0.94 |
| HOMA-IR | 3.39(2.59) | 2.79(2.14) | 3.93(2.56) | 3.33(2.86) | −0.60 (−1.21~0.01) | 0.70 |
| TC(mmol/L) | 4.93(0.76) | 4.83(0.84) | 4.96(1.02) | 4.57(0.76) | −0.33(−0.54~ − 0.12) | 0.69 |
| TG(mmol/L) | 2.16(1.98) | 2.55(3.69) | 2.74(2.42) | 2.19(0.95) | −0.03(− 0.82~0.76) | 0.91 |
| HDL(mmol/L) | 1.06(0.21) | 1.00(0.19) | 1.14(0.29) | 1.09(0.24) | −0.04(− 0.09~0.01) | 0.70 |
| LDL(mmol/L) | 3.29(0.83) | 2.95(0.65) | 3.14(0.51) | 2.87(0.63) | −0.31(− 0.51~ − 0.11) | 0.86 |
| SBP(mmHg) | 126.00(13.23) | 128.86(14.78) | 128.80(15.88) | 123.90(14.45) | −2.41(−8.75~3.93) | 0.34 |
| DBP(mmHg) | 81.21(7.10) | 82.64(11.02) | 81.60(10.28) | 78.15(9.09) | 0.88(−5.23~7.03) | 0.56 |
| BMI(kg/m2) | 28.26(4.93) | 27.68(3.82) | 28.36(2.85) | 27.82(3.35) | −0.67(−1.05~ − 0.30) | 0.38 |
| WHR | 0.96(0.01) | 0.95(0.01) | 0.97(0.06) | 0.97(0.05) | −0.01(−0.03~0.01) | 0.67 |
Abbreviations: OSA, obstructive sleep apnea; EDS, excessive daytime sleepiness; BMI, body mass index; HOMA-IR, homeostasis model of assessment for insulin resistance index; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; SBP, systolic blood pressure; DBP, diastolic blood pressure