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. 2019 Dec 4;10:373. doi: 10.1186/s13287-019-1486-4

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 11 — Contractile function using different hCSC line. a Developed force, b rate of contraction (+dF/dt), and c rate of relaxation (−dF/dt), for hCM-only controls (red circle) (n = 5), and hCSC-supplemented hECTs (blue triangle) (n = 7), at day 6 after tissue fabrication. d Developed force at day 8 (n = 5 and n = 6 respectively) and day 10 (n = 4 and n = 8 respectively) after tissue fabrication. Measurements performed at 1.0-Hz pacing frequency; values normalized to mean control hECTs. Dot plots show individual data with bars representing mean ± SD; ***p < 0.001