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. 2019 Dec 4;10:373. doi: 10.1186/s13287-019-1486-4

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Time course of hECT twitch force. a Developed force at 0.75-Hz pacing at 6, 8, and 10 days after tissue fabrication for hCM-only control hECT (red circle) and hCSC-supplemented hECT (blue triangle). b Corresponding passive (diastolic) force from the same twitches analyzed for panel a. c Cross-sectional area of the hECT calculated from tissue diameter measured by digital image analysis immediately before twitch testing. d Developed stress (force/area) calculated from data in panels a and c. Dot plots show individual data with bars representing mean ± SD; all values normalized to mean hCM-only control at corresponding time point; *p < 0.05, **p < 0.01, ***p < 0.001