Table 1.
List of genes included in NanoString Codeset
| Gene symbol | Gene name | Fold change* | p value |
|---|---|---|---|
| ACTA1 | Actin, Alpha 1, Skeletal Muscle | 2.35 | 0.0030 |
| ACTA2 | Actin, Alpha 2, Smooth Muscle, Aorta | 1.17 | 0.3664 |
| ACTN2 | Actinin Alpha 2 | 1.00 | 0.9877 |
| ADRB1 | Adrenoceptor Beta 1 | 1.39 | 0.2645 |
| ADRB2 | Adrenoceptor Beta 2 | 1.35 | 0.2586 |
| ADRB3 | Adrenoceptor Beta 3 | 0.84 | 0.7008 |
| AGTR1 | Angiotensin II Receptor Type 1 | 0.34 | 0.0214 |
| ATP2A2 | ATPase Sarcoplasmic/Endoplasmic Reticulum Ca2+ Transporting 2 | 0.95 | 0.6659 |
| BAX | BCL2 Associated X, Apoptosis Regulator | 1.11 | 0.6011 |
| BCL2 | BCL2, Apoptosis Regulator | 0.57 | 0.1837 |
| BCL2L1 | Apoptosis Regulator Bcl-X | 1.08 | 0.7545 |
| BCL2L2 | Apoptosis Regulator Bcl-W | 0.88 | 0.5770 |
| CACNA1C | Voltage-Gated L-Type Calcium Channel Cav1.2 Alpha 1 Subunit | 1.06 | 0.8099 |
| CASP3 | Caspase 3 | 0.79 | 0.0175 |
| CASP8 | Caspase 8 | 0.70 | 0.4188 |
| CASP9 | Caspase 9 | 1.05 | 0.8472 |
| CASQ2 | Calsequestrin 2 | 0.49 | 0.0902 |
| CD34 | CD34 Molecule | 1.15 | 0.1137 |
| CD44 | CD44 Molecule (Indian Blood Group) | 2.28 | 0.2705 |
| CDK1 | Cyclin Dependent Kinase 1 | 0.39 | 0.0043 |
| CNTN2 | Contactin 2 | 0.53 | 0.2429 |
| COL1A1 | Collagen Type I Alpha 1 Chain | 2.18 | 0.0254 |
| COL3A1 | Collagen Type III Alpha 1 Chain | 1.74 | 0.0151 |
| CTGF | Connective Tissue Growth Factor | 1.13 | 0.5425 |
| DDR2 | Discoidin Domain Receptor Tyrosine Kinase 2 | 0.86 | 0.5965 |
| ENG | Endoglin (CD105) | 2.04 | 0.1706 |
| GATA 4 | GATA-Binding Factor 4 | 1.25 | 0.0533 |
| GJA1 | Connexin-43 (Gap Junction Protein Alpha 1) | 0.88 | 0.2805 |
| GJA5 | Gap Junction Protein Alpha 5 (Connexin 40) | 0.58 | 0.1210 |
| HCN1 | Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 1 | 0.40 | 0.0024 |
| HCN2 | Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 2 | 1.43 | 0.6689 |
| HCN3 | Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 3 | 0.95 | 0.9201 |
| HCN4 | Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4 | 1.16 | 0.4744 |
| IRX4 | Iroquois Homeobox 4 | 0.96 | 0.7108 |
| JUP | Junction Plakoglobin | 1.01 | 0.9708 |
| KCNH2 | HERG1 - Ether-A-Go-Go-Related Gene Potassium Channel 1 | 1.12 | 0.6170 |
| KCNQ1 | Potassium Voltage-Gated Channel Subfamily Q Member 1 (Kv7.1) | 1.87 | 0.1707 |
| MESP1 | Mesoderm Posterior BHLH Transcription Factor 1 | 2.34 | 0.3436 |
| MYC | C-Myc | 1.73 | 0.3395 |
| MYH6 | Myosin Heavy Chain 6 | 0.74 | 0.0216 |
| MYH7 | Myosin Heavy Chain 7 | 1.24 | 0.2239 |
| MYL2 | Cardiac Ventricular Myosin Light Chain 2 (MLC-2v) | 1.53 | 0.1215 |
| MYL7 | Myosin Regulatory Light Chain 2, Atrial Isoform (MLC-2A) | 0.69 | 0.0009 |
| NFATC1 | Nuclear Factor Of Activated T Cells 1 | 2.19 | 0.1411 |
| NKX2–5 | Cardiac-Specific Homeobox | 1.19 | 0.1061 |
| NPPA | Natriuretic Peptide A | 1.78 | 0.0013 |
| NPPB | Natriuretic Peptide B | 1.64 | 0.0154 |
| PECAM1 | Platelet And Endothelial Cell Adhesion Molecule 1 (CD31) | 1.55 | 0.1507 |
| PLN | Phospholamban | 1.37 | 0.0199 |
| POSTN | Periostin | 3.82 | 0.1770 |
| RYR2 | Ryanodine Receptor 2 | 0.82 | 0.0621 |
| SLC8A1 | Sodium/Calcium Exchanger 1 (NCX1) | 1.09 | 0.1813 |
| TGFB1 | Transforming Growth Factor Beta 1 | 2.14 | 0.0262 |
| TNNI1 | Troponin I1, Slow Skeletal Type | 0.98 | 0.9204 |
| TNNI3 | Troponin I3, Cardiac Type | 1.90 | 0.0009 |
| TP53 | Tumor Protein P53 | 1.01 | 0.9708 |
| VIM | Vimentin | 0.86 | 0.2823 |
| WT1 | Wilms Tumor 1 | 0.56 | 0.1367 |
Listed alphabetically according to gene symbol. Expression level (fold change relative to control*) and p value for hCSC-supplemented hECTs normalized to hCM-only control hECTs