Table 1.

Patient characteristics and number of genomic alterations detected in ctDNA among pancreatic ductal adenocarcinoma patients (N = 112)

Characteristics for all patients [N = 112]		N (%)
Median age (range) (years)*		67.8 (38.0–92.7)
Gender
Men		60 (53.6%)
Women		52 (46.4%)
Ethnicity
Caucasian		76 (67.9%)
Hispanic		16 (14.3%)
Asian		7 (6.3%)
African American		4 (3.6%)
Other/unknown		9 (8.0%)
Disease status at the time of blood draw
Advanced (metastatic, locally advanced or recurrent disease)		94 (83.9%)
Preoperative (surgically resectable, blood obtained before surgery)		10 (8.9%)
Postoperative (surgically resectable, blood obtained after surgery)		8 (7.1%)
Number of patients with ≥ 1 characterized alteration		78 (69.6%)
Median number of characterized alterations per patient (range)		1 (0–6)
Comparisons of ctDNA results between advanced cases and preoperative cases**
Parameters	Advanced cases (N = 94)	Preoperative cases (N = 10)	P value
Number of characterized alterations per patient (range), median (range) (%)	2 (0–6)	0.5 (0–3)	0.04
No. of patients with detectable characterized alterations	70 (74.5%)	5 (50.0%)	0.14
Maximum %ctDNA per patient (characterized alterations), median (range) (%)	0.4 (0.0–64.6)	0.0 (0.0–0.62)	0.02
Total %ctDNA per patient (characterized alterations), median (range) (%)	0.6 (0.0 - 92.05)	0.0 (0.0 - 0.70)	0.007

*Age at date of advanced disease diagnosis or date of first diagnosis for surgically resectable diseases

**Postoperative cases (blood obtained after radical surgery) were not included in these comparisons