Table 5.
Histo-type | Variable | Univariate analysis (log-rank test) | Multivariate analysis (Cox regression) | Univariate analysis (log-rank test) | Multivariate analysis (Cox regression) | ||||
---|---|---|---|---|---|---|---|---|---|
5-year OS | P | HR (95% CI) | P | 5-year CSS | P | HR (95% CI) | P | ||
Chondrosarco-ma, NOS | Radiotherapy | 0.642 | 0.709 | ||||||
Performed | 27.8% | 32.0% | |||||||
Not performed | 31.0% | 37.1% | |||||||
Treatment | 0.064 | 0.085 | |||||||
Both | 27.9% | 40.8% | |||||||
Surgery only | 34.9% | 39.1% | |||||||
Radiotherapy only | 1.0% | 1.4% | |||||||
None | 8.0% | 11.5% | |||||||
Myxoid | Radiotherapy | 0.608 | 0.211 | ||||||
Performed | 42.7% | 52.9% | |||||||
Not performed | 28.6% | 28.6% | |||||||
Treatment | 0.000 | 0.000 | |||||||
Both | 45.6% | 58.0% | |||||||
Surgery only | 30.8% | 30.8% | |||||||
Radiotherapy only | NA* | NA* | |||||||
None | NA* | NA* | |||||||
Mesenchymal | Radiotherapy | 0.934 | 0.883 | ||||||
Performed | 53.7% | 59.7% | |||||||
Not performed | 56.7% | 60.2% | |||||||
Treatment | 0.703 | 0.380 | |||||||
Both | 60.9% | 69.6% | |||||||
Surgery only | 61.4% | 65.1% | |||||||
Radiotherapy only | 1.0% | 1.0% | |||||||
None | 33.3% | 33.3% | |||||||
Dedifferentiated | Radiotherapy | 0.020 | 0.005 | ||||||
Performed | 50.2% | Reference | 58.3% | Reference | |||||
Not performed | 20.6% | 2.64 (1.17–5.95) | 0.019 | 21.5% | 3.56 (1.39–9.15) | 0.008 | |||
Treatment | 0.015 | NA# | 0.007 | NA# | |||||
Both | 53.3% | 61.9% | |||||||
Surgery only | 23.6% | 24.3% | |||||||
Radiotherapy only | NA* | NA* | |||||||
None | NA* | NA* |
SEER – Surveillance, Epidemiology, and End Results; OS – overall survival; CSS – cancer-specific survival; HR – hazard ratio; CI – confidence interval; NOS – not otherwise specified;
NA* – the analysis is not available because of the small sample size;
NA# – the analysis is not available because of the covariance.