Table 4:

Mixed Effects model of association between cannabis and time on alcohol use: moderation by alcohol substitution reason among medicinal users.

	Estimate	SE	p-value	Lower CI	OR	Upper CI

Intercept	−1.22	0.83	–	–	–	–
Any cannabis use^a	−0.21	0.07	<.01	0.71	0.81	0.93
Substitution reason	0.21	0.12	0.10	0.97	1.23	1.56
Time^a	0.0002	0.0001	0.26	1.00	1.0001	1.0004
% cannabis use days	0.0004	0.005	0.94	0.99	1.0004	1.01
Any cig^a	0.57	0.05	<.001	1.59	1.76	1.95
Any other drug^a	2.09	0.16	<.001	5.94	8.10	11.06
Weekend^a	0.59	0.029	<.001	1.70	1.80	1.91
Baseline age	0.06	0.02	0.03	1.01	1.06	1.11
Any cannabis use^a × substitution reason	−0.23	0.04	<.001	0.73	0.79	0.86
Any cannabis use^a × time^a	0.0004	0.0002	0.04	1.00002	1.0004	1.001
Substitution reason × time^a	−0.0003	0.0001	<.01	0.9995	0.9997	0.9999
Any cannabis use^a × substitution reason × time^a	0.001	0.0001	<.001	1.0004	1.0007	1.001

Note. This analysis was conducted in the subsample of medicinal users only (n =64; 34,560 observations); Coefficients are unstandardized.

Denotes time-varying.