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. Author manuscript; available in PMC: 2019 Dec 5.
Published in final edited form as: J Hum Genet. 2018 Jan 30;63(4):431–446. doi: 10.1038/s10038-017-0403-x

Fig. 3.

Fig. 3

Genetic and functional evidence suggesting LOC157273 to be a lipid susceptibility gene. a The regional association plots show the association of variants in LOC157273 with HDL and LDL cholesterol. b A figure generated by the UCSC Genome Browser on 8p23.1 locus hosting LOC157273. The position of SNP rs4841132 within the second exon of LOC157273 and CpG site cg17371580 within the conserved promoter region of lncRNA are depicted by red arrows. The figure also illustrates the expression of LOC157273 across different tissues using the Human Body Map catalog, indicating that the lncRNA is expressed in liver. c A schematic showing the lncRNA structure, the nearest protein coding gene PPP1R3B, the position of SNPs and a CpG site in the lncRNA associated with lipid traits.