Figure 1. Molecular characterization of two types of serrated CRC: classical and mesenchymal.
Typical molecular features of the two types (“Classical (left)” vs “Mesenchymal (right)”) of serrated CRC proposed in this review based on the previously reported evidence. CIMP, CpG island methylation phenotype; CRC, colorectal cancer; MSI-H, microsatellite instability-high; MSI-H, microsatellite instability-low; MSS, microsatellite stable.