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. Author manuscript; available in PMC: 2020 Nov 15.
Published in final edited form as: Neuroimage. 2019 Aug 28;202:116138. doi: 10.1016/j.neuroimage.2019.116138

Figure 8.

Figure 8.

Independent component analysis of resting state functional MRI revealed significant effects of Aβ and IL6 on hippocampal, thalamic, midbrain and striatal networks. A) Eight of 20 components were consistent with established ICA networks in mice. Shown here are 8, which include anterior cingulate, motor, somatosensory, retrosplenial, midbrain, thalamic, and hippocampal regions (t>2.3). B) Comparison of a thalamic/midbrain component in 4 experimental groups. C) Components that had significant main effects of Aβ, IL6, or Aβ × IL6 interactions following permutation tests (p<0.05 family-wise error corrected).