Table 2.
Statistically significant ≥10% changes of 10 cytokines in the propofol group
| Cytokine | Baseline pg/ml [median (IQR)] | Anesthesia pg/ml [median (IQR)] | Unadjusted p-value | Adjusted p-value |
|---|---|---|---|---|
| PDGF | 2160 (460) | 2625 (971) | 0.002 | 0.02 |
| IP-10 | 332 (188) | 289 (112) | 0.004 | 0.03 |
| IL-5 | 6 (1) | 8 (2) | 0.006 | 0.03 |
| IL-7 | 10 (4) | 11 (3) | 0.005 | 0.03 |
| IL-17 | 158 (60) | 175 (71) | 0.008 | 0.03 |
| MIG | 245 (81) | 201 (69) | < 0.001 | 0.01 |
| HGF | 156 (24) | 129 (33) | 0.002 | 0.02 |
| MCP-1 | 38 (16) | 31 (14) | 0.004 | 0.03 |
| CTACK | 598 (270) | 534 (168) | 0.005 | 0.03 |
| MIF | 227 (159) | 113 (82) | < 0.001 | 0.01 |
Data were analyzed using nonparametric testing due to the skewed distributions and the outlying observations. The median as well as the inter quartile range (IQR) values are reported for each cytokine. The unadjusted p-values were calculated using Wilcoxon signed rank test and the adjusted p-values were calculated using Benjamini-Hochberg method (42 hypothesis tests) controlling for a false discovery rate at 0.05