Fig 7. Detection of CP24 or IBP-CP24-specific antibody in the plasma of rhesus monkeys intravenously administered with CP24 or IBP-CP24 by indirect ELISA and effect of the peptides on antibody-mediated ADCC.
(A) CP24 or IBP-CP24-specific antibody response in the CP24- or IBP-CP24-treated rhesus monkeys. The level of CP24 or IBP-CP24-specific IgG in the plasma of rhesus monkeys intravenously administered with PBS, CP24 or IBP-CP24 by indirect ELISA. The data were presented as mean ± SD. (B) Specific lysis of H9/HIV-1IIIB-infected cells mediated by 10E8 and PBMC via antibody-dependent cell-mediated cytotoxicity (ADCC). Each sample was tested in triplicate and data were presented as mean ± SD. Unpaired, 2-tailed t test was performed. ns, no significance.