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. 2019 Dec 5;14(12):e0225824. doi: 10.1371/journal.pone.0225824

Table 2. Overview of transition time (T50) expressed in minutes.

T50 in minutes A1.5 A1.25 C1.5 P-value# Post-hoc (p-value, pairwise)*
1 2 3
Predialysis 1st 284 [235–346] 274 [213–308] 271 [234–291]
2nd 294 [230–331] 291 [239–339]] 282 [244–308]]
3rd 300 [247–335] 307 [256–337] 280 [262–339]
Median` 290 [251–323] 308 [256–337] 289 [251–320] 0.22
p-value# 0.33 <0.001 0. 002
Postdialysis 1st 351 [318–399] 380 [322–400]] 408 [348–455]]
2nd 357 [337–397] 360 326–413]] 405 [352–451]
3rd 349 [316–401] 376 [327–404]] 415 [364–479]
Median 353 [323–405] 358 [327–413] 395 [368–462] <0.001 0.08 <0.001 <0.001
p-value# 0.42 0.32 0.23
Delta 1st 72 [1–97] 92 [68–124] 121 [86–168]
2nd 89 [28–118] 75 [43–98] 115 [92–148]
3rd 53 [19–97] 74 [34–98] 115 [84–150]
Median 66 [18–102] 83 [43–108] 121 [90–152] <0.001 0.09 <0.001 <0.001
p-value# 0.34 0.001 0.15

Note: Data are expressed as median with 25th and 75th percentile, sorted by session and in total.

`Median were calculated for predialysis from second and third session.

#P-values were calculated with Friedman test.

*Post-hoc p-values were calculated with Wilcoxon Signed Rank test as pairwise comparisons and a p-value <0.017 was considered statistically significant based on Bonferroni correction. A1.5 = acetic-acid dialysate with 1.50mmol/l calcium, A1.25 = acetic-acid dialysate with 1.25mmol/l calcium, C1.5 = citric-acid dialysate with 1.50mmol/l calcium. 1 = A1.5 vs. A1.25; 2 = A1.5 vs. C1.5; 3 = A1.25 vs. C1.5.