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. 2019 Dec 5;14(12):e0225181. doi: 10.1371/journal.pone.0225181

Table 2. Clinical variables at baseline and at 2 minutes of the spontaneous breathing trial.

Baseline 2 min p valuea
Heart Rate (beats/min)
 Weaning Success 86 ± 18 87 ± 18 <0.001
 Extubation failure 96 ± 18 94 ± 13 0.52
Systolic arterial blood pressure (mmHg)
 Weaning Success 132 (121–151) 137 (121–156) 0.001
 Extubation failure 136 (130–146) 130 (123–159) 0.42
CVP (mmHg)
 Weaning Success 10 (7–13) 10 (6–12) 0.018
 Extubation failure 8 (6–12) 12 (9–16) 0.001
dCVP (mmHg)
 Weaning Success 0 (-2-0.5) <0.0001§
 Extubation failure 3 (2–4)
Respiratory Rate (breaths/min)
 Weaning Success 18 (15–22) 20 (17–24) <0.001
 Extubation failure 18 (13–25) 19 (17–24) 0.08
SaO2 (%)
 Weaning Success 96 (95–98) 97 (95–99) 0.33
 Extubation failure 97 (95–98) 96 (93–100) 0.83

Continuous variables are expressed as mean ± SD or median (interquartile range)

SBT spontaneous breathing trial, CVP central venous pressure, dCVP change in CVP from baseline to 2-minutes after starting SBT, SaO2 arterial oxygen saturation.

ap values represent statistical comparisons between variables comparing 2 min to baseline by paired t-test or Wilcoxon rank-sum test as appropriate.

§ p-value compares dCVP at 2 minutes between groups