Table 1. Characteristics of the 2,196 consecutive patients admitted with clinical suspicion of bacterial infection and receiving intravenous antibiotic treatment within 48 hours of admission.

Results for all patients and for those with severe sepsis and Sepsis-3 sepsis respectively.

Characteristics	Clinically suspected bacterial infection N (%)	Severe Sepsis N (%)	Not severe sepsis N (%)	p-value	Sepsis-3 sepsis N (%)	Not Sepsis-3 sepsis N (%)	p-value
Individuals	2,196	429 (20)	1,767 (80)		1,299 (59)	897 (41)
Age, years, mean (SD)	69 (18)	74 (15)	67 (19)	<0.001	74 (15)	61 (20)	<0.001
Age, years, median (IQR)	73 (60–83)	78 (68–85)	72 (57–81)	<0.001	78 (67–85)	65 (47–77)	<0.001
Males	1,199 (55)	298 (53)	801 (55)	ns	708 (55)	491 (54)	ns
No co–morbidities	359 (16)	37 (9)	322 (18)	<0.001	119 (9)	240 (27)	<0.001
Chronic cardiovascular disease	1,183 (54)	274 (64)	909 (51)	<0.001	824 (63)	359 (40)	<0.001
Chronic lung disease	352 (16)	75 (18)	277 (16)	ns	263 (20)	89 (10)	<0.001
Chronic kidney disease	153 (7)	31 (7)	122 (7)	ns	87 (7)	62 (7)	ns
Chronic liver disease	13 (.6)	2 (.5)	11 (.6)	ns	8 (1)	5 (1)	ns
Diabetes mellitus	375 (17)	105 (25)	270 (15)	<0.001	257 (20)	118 (13)	<0.001
Malignancy <5 years	377 (17)	80 (19)	297 (17)	ns	241 (19)	136 (15)	0.002
Immunosuppression	106 (5)	20 (5)	86 (5)	ns	55 (4)	51 (6)	ns
Other	706 (32)	162 (38)	544 (31)	0.012	432 (33)	274 (30)	ns
Patients with multiple admissions N (column %)
1 admission	1,982 (90)	392 (84)	1,590 (89)		1,154 (89)	828 (92)
2 admissions	169 (8)	29 (13)	140 (8)		116 (9)	53 (6)
3 admissions	39 (2)	7 (3)	32 (2)		25 (2)	14 (2)
≥4 admissions	6 (.5)	1 (.6)	5 (.2)		4 (.4)	2

SD, Standard Deviation; IQR, Interquartile range; SOFA, Sequential Organ Failure Assessment (score); ns, not significant.