TABLE II.

Analysis of Change in Gene Expression Relative to β-Actin Adjusting for Age

			HSP90 vs. β-Actin		LEDGF/p75a vs. β-Actin		P21 vs. β-Actin		APOBEC3G vs. β-Actin
Group	Total	No. (%)	Fold change	P-value	Fold change	P-value	Fold change	P-value	Fold change	P-value
Gender	49
Female		35 (71.4)	Ref		Ref		Ref		Ref
Male		14 (28.6)	1.05	0.68	1.02	0.69	−1.14	0.70	1.73	0.23
Ethnicity	49
Hispanic		40 (83.3)	Ref		Ref		Ref		Ref
Not Hispanic		9 (18.4)	1.06	0.68	1.04	0.61	−1.18	0.67	1.45	0.48
Infection status	49
Uninfected		16 (32.7)	Ref		Ref		Ref		Ref
Infected		33 (67.3)	−1.43	0.01	−1.26	0.001	2.35	0.03	−4.71	0.003

Note: The fold changes were obtained from the 2^−ΔΔCt method in multiplicative effect. Ref, Reference group.

^aLEDGF/p75 was transformed by the natural log in all models to better meet the residual normality criterion of linear regression.

The bold face highlights the significant p-values.