Table 1.
List of structurally-characterized antibodies in complex with pneumovirus F proteins or fragments thereof.
| mAb | PDB ID | Origin | Antigenic site | References |
|---|---|---|---|---|
| RSV F | ||||
| motavizumab | 3IXT, 3QWO, 4JLR, 6OE5, 4ZYP | Mouse | II | (44) |
| 101F | 3O41, 3O45 | Mouse | IV | (45) |
| hRSV90 | 5TPN | Human | V | (46) |
| D25 | 4JHW | Human | Ø | (36) |
| MEDI8897 | 5UDC, 5UDD | Human | Ø | (47) |
| AM22 | 6DC5, 6APD | Human | Ø | (48) |
| 5C4 | 5W23 | Mouse | Ø | (49) |
| MPE8 | 5U68 | Human | III | (50) |
| ADI19425 | 6APD | Human | III | (51) |
| CR9501 | 6OE4/6OE5 | Human | V | (52) |
| AM14 | 4ZYP | Human | IV, V | (53) |
| RSD5 | 6DC3 | Human | Ø | (48) |
| 14N4 | 5J3D | Human | II | (54) |
| ADI14359 | 6APD | Human | I | (51) |
| R4.C6 | 6CXC | Mouse | II, IV | (55) |
| RB1 | 6OUS | Human | IV | (56) |
| F-VHH-4 | 5TOJ | Llama | II, III, IV, V | (57) |
| F-VHH-L66 | 5TOK | Llama | II, III, IV, V | (57) |
| hMPV F | ||||
| DS7 | 4DAG | Human | DS7-site | (38) |