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. 2019 Dec 5;9:18390. doi: 10.1038/s41598-019-54739-1

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Lung water content (A) and Evans blue dye extravasation (B) in different groups of rats. All heated groups were exposed to heat for exactly 80 min and then allowed to recover at room temperature. Data are presented as the mean ± SD of 10 rats per group. ^bP < 0.05, V + heated group vs. V + nonheated group; ^eP < 0.05, V + OT + heated group vs. V + heated group; ^dP < 0.05, L-368,899 + OT + heated group vs. V + OT + heated group.