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. 2019 Dec 5;3:31. doi: 10.1038/s41698-019-0105-2

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — H&E and Ki67 staining of tumor sections obtained from the single mouse trial. a Representative images of the H&E and Ki67 stained tumor sections from different treatment groups displayed comparatively higher antiproliferative activity of EG-L. Bar length = 200 µm. b, c Quantification of Ki67-positive nuclei in 786-O and A498 tumor sections, respectively. Error bars in all graphical plots are given based on standard deviation. *, ** and *** denote p < 0.05, p < 0.01, and p < 0.001 compared to control, respectively (n = 5 spatially different regions from same tumor section).