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. 2019 Dec 5;9:18427. doi: 10.1038/s41598-019-54965-7

Table 1.

ROC curve analysis of qualitative prediction of AMI/R and necrosis.

Metabolites AUC (95% CI) Youden index Sensitivity Specificity
AMI/R – Sham
   Lac/Bicar 0.95 (0.77–0.99) 0.88 87.50 100.00
   Lac/tC 0.91 (0.73–0.98) 0.69 100.00 68.75
   Bicar/Lac + Ala 0.88 (0.68–0.98) 0.69 75.00 93.75
   Bicar/tC 0.71 (0.51–0.88) 0.44 87.50 56.25
Necrosis – Sham
   Lac/Bicar 1.00 (0.86–1.00) 1.00 100.00 100.00
   Lac/tC 0.87 (0.67–0.97) 0.63 62.50 100.00
   Bicar/Lac + Ala 1.00 (0.86–1.00) 1.00 100.00 100.00
   Bicar/tC 0.90 (0.70–0.98) 0.56 87.50 68.75
Necrosis – AMI/R
   Lac/Bicar 0.92 (0.68–0.99) 0.88 87.50 100.00
   Lac/tC 0.64 (0.37–0.86) 0.50 62.50 87.50
   Bicar/Lac + Ala 0.95 (0.71–0.99) 0.88 87.50 100.00
   Bicar/tC 0.78 (0.51–0.95) 0.50 51.00 100.00