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. 2019 Jul 5;47(16):8548–8562. doi: 10.1093/nar/gkz568

Figure 1.

Figure 1.

CSB-deficiency leads to nucleosome decondensation. (A) DAPI staining of CSA-deficient CS3BE (CSA−) and CSB-deficient CS1AN (CSB−) cells with their respective corrected cells, which stably expressing wild-type CS proteins (CSA+ and CSB+). (B and C) Quantification of DAPI signal from A. CTCF, corrected total cell fluorescence. Error bars represent mean ± SEM. ***, <0.001; NS, not significant. (D) CS (CSA− and CSB−) cells and their respective corrected (CSA+ and CSB+) cells were lysed and probed for the indicated proteins on western blot. (E) Doxycycline-inducible CSA and CSB knockdown cells (iKD) were probed for indicated proteins on western blot after 72 h of doxycycline treatment.