Fig. 8.

Photographs of liver tissue. We observed the Hepatoprotective effect of EA against MTX-induced liver injury (n = 3). (a) Control group showed normal architecture. (b) Extensive necrosis, degeneration and inflammation of hepatocytes in MTX group. (c) Co-treatment of MTX and EA 5 showed moderate inflammation. (d) EA 10 treatment caused just minor pathological alterations in MTX-administered rats. EA, Ellagic acid; MTX, Methotrexate. Arrow indicates Inflammation, Arrow head indicates eosinophilic cells, Asterisk indicates vacuolization of cells. Original magnification ×20