Table 2.
Groups | Histological score | Degenerative changes |
---|---|---|
Control | 1 | No abnormality |
MTX | 5 | Extensive pathologic changes such as prominent granular degeneration, inflammation, eosinophilic cells, vacuolation etc. |
MTX + EA 5 mg/kg | 3 | Moderate pathologic changes such as Inflammation |
MTX + EA 10 mg/kg | 2 | Mild pathological changes |
1: No abnormality 2: Mild degenerative changes (10%). 3: Moderate degenerative changes (25%). 4: Severe degenerative changes (50%). 5: Extensive and marked changes (>75%)