Table 1.

Patient baseline characteristics, and treatment and bleed history, by hemophilia type

	HA	HAwI	HBwI
Patients, N*	36	9	8
Mean age at baseline (SD), y	36.9 (12.9)	38.0 (12.1)	29.8 (8.5)
Mean body weight (SD), kg	77.0 (20.4)	75.3 (13.8)	67.1 (10.2)
Mean time from diagnosis (SD), y	34.4 (12.1)	37.4 (12.8)	29.0 (8.5)
Patients on prophylaxis, n	31	1	1
Prophylaxis mean ABR (min; max)	5.2 (0; 52)	8.6	0.0
Patients treated on demand, n	10	9	8
On-demand mean ABR (min; max)†	17.5 (4; 47)	17.2 (6; 39)	34.3 (6; 120)
On-demand median ABR	10	18	24

Patient baseline characteristics and treatment and bleed history by hemophilia type in explorer4 (HAwI, HBwI) and explorer5 (HAwI) (concizumab-treated patients only; full analysis set).

max, maximum; min, minimum; SD, standard deviation.

^*Patients were permitted to be treated with >1 treatment regimen during the 12 months prior to screening.

^†During the treatment regimen.