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. 2019 Aug 23;134(22):1973–1982. doi: 10.1182/blood.2019001542

Table 2.

Concizumab dose escalation by hemophilia type

HA HAwI HBwI
N 36 9 8
Dose escalation, n (%)
 None: 0.15 mg/kg only 21 (58.3) 8 (88.9) 7 (87.5)
 One: 0.15 and 0.20 mg/kg 7 (19.4) 1 (11.1) 1 (12.5)
 Two: 0.15, 0.20, and 0.25 mg/kg 8 (22.2) 0 (0.0) 0 (0.0)

Concizumab dose escalation by hemophilia type in explorer4 (HAwI/HBwI) and explorer5 (HAwI) (concizumab-treated patients only; full analysis set).