Table 3.
Clinical features of patients evaluated for typhoid fever in Enugu, Nigeria
| Parameter | Typhoid suspects N= 810 n (%) |
Typhoid culture [+ve] N=114 n (%) |
Typhoid culture [−ve] N=696 n (%) |
P-value |
| Fever | 810 (100.0) | 114 (100.0) | 696 (100.0) | 1.00 |
| Headache | 641 (79.1) | 87 (76.3) | 554 (79.6) | 0.42 |
| Anorexia | 553 (68.3) | 89 (78.1) | 464 (66.7) | 0.02 |
| Diarrhoea | 470 (58.0) | 72 (63.2) | 398 (57.2) | 0.23 |
| Constipation | 130 (16.0) | 27 (23.7) | 104 (14.9) | 0.02 |
| Abdominal discomfort/pain |
432 (53.3) | 102 (89.5) | 330 (47.4) | <0.001 |
| Vomiting | 384 (47.4) | 62 (54.4) | 322 (46.3) | 0.12 |
| Pallor | 93 (11.5) | 11 (9.6) | 82 (11.8) | 0.51 |
| Jaundice | 19 (2.3) | 2 (1.8) | 17 (2.5) | 0.65 |
| Hepatomegaly | 125 (15.4) | 23 (20.2) | 102 (14.7) | 0.13 |
| Splenomegaly | 45 (5.6) | 20 (17.5) | 25 (3.6) | <0.001 |
| Tachycardia | 404 (49.9) | 58 (50.9) | 346 (49.7) | 0.82 |
| Relative bradycardia | 23 (2.8) | 14 (12.3) | 9 (1.3) | <0.001 |