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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: Addict Biol. 2019 Jun 6;25(4):e12779. doi: 10.1111/adb.12779

Figure 1. Exposure to dietary yeast paste alters ethanol sedation sensitivity.

Figure 1

(A) w[A] females fed a paste of live or dead yeast (35% w/v) for 2 d took longer to become sedated compared to flies fed 2Y10S3C (standard) medium (two-way ANOVA; time, p<0.0001; yeast, p<0.0001; interaction, p<0.0001; *Bonferroni’s multiple comparisons (BMC) versus 2Y10S3C; p<0.0001; n=7–8 per data point). (B) ST50 values derived from panel A. Yeast (Y) paste had a significant overall effect on ST50s (one-way ANOVA, p<0.0001, n=7–8). ST50s were greater in flies fed live or dead yeast versus 2Y10S3C medium (*BMC, p<0.0001). ST50s were not distinguishable between flies fed live or dead yeast paste (BMC, p=0.9682). (C) Dietary yeast paste increased ST50 values in r[A] females (two-way ANOVA; yeast, p<0.0001; time, p=0.0029; interaction, p=0.3486; *BMC, p=0.0136 to <0.0001; n=8).