Figure 1: Maternal cocaine exposure prior to conception alters maternal behavior.
A. Dams self-administered cocaine for 60 consecutive days followed by a 10 day drug-free washout period. They were then paired with drug naïve males to produce F1 offspring. B. Cocaine-exposed dams showed significant changes in a range of maternal and passive behaviors. * p<0.0001. C. Average time spent on each behavior in saline vs. cocaine dams.