Table 2:
Event Characteristics by Cardiac Illness Category
| Illness Category |
||||
|---|---|---|---|---|
| Variable | Overall (N = 113) |
Surgical cardiac (N = 88) |
Medical cardiac (N = 25) |
P-value |
| Average over (up to) the first 10 minutes | ||||
| Chest compression rate (/min) | 127.1 [114.5,139.2] | 128.4 [113.9,140.2] | 122.7 [117.5,129.8] | 0.2172 |
| DBP (mmHg) | 27.7 [22.0,36.5] | 26.4 [21.9,34.8] | 33.0 [27.4,42.0] | 0.0312 |
| DBP (mmHg) ≥ 25 for infants or ≥30 for children | 68 (60.2%) | 51 (58.0%) | 17 (68.0%) | 0.4881 |
| SBP (mmHg) | 69.3 [53.0,93.2] | 66.3 [50.9,87.6] | 79.0 [67.6,100.0] | 0.0372 |
| SBP (mmHg) ≥ 60 for infants or ≥ 80 for children | 61 (54.0%) | 47 (53.4%) | 14 (56.0%) | 1.0001 |
| MAP (mmHg) | 43.0 [33.9,54.5] | 42.5 [33.0,50.7] | 48.3 [38.7,60.7] | 0.0232 |
| Ventilation rate (/min)3 | 32.7 [24.9,37.4] | 34.9 [30.2,48.4] | 24.9 [20.2,33.1] | 0.0432 |
| ETCO2 (mmHg)3 | 15.8 [9.4,25.2] | 10.9 [8.7,20.5] | 24.7 [16.4,26.3] | 0.1492 |
| Chest compression fraction | 0.9 [0.8,1.0] | 0.9 [0.8,1.0] | 0.9 [0.8,0.9] | 0.5072 |
| Outcomes | ||||
| ROSC ≥ 20 min | 74 (65.5%) | 59 (67.0%) | 15 (60.0%) | 0.6341 |
| ROC with eCPR | 33 (29.2%) | 29 (33.0%) | 4 (16.0%) | 0.1361 |
| Survival to hospital discharge | 57 (50.4%) | 49 (55.7%) | 8 (32.0%) | 0.0431 |
| Neurologic outcomes in survivors (N=57) | ||||
| Favorable neurologic outcome based on PCPC4 | 53 (93.0%) | 45 (91.8%) | 8 (100.0%) | 1.0001 |
| Pediatric Cerebral Performance Category at hospital discharge | 0.0802 | |||
| Normal | 21 (36.8%) | 20 (40.8%) | 1 (12.5%) | |
| Mild disability | 21 (36.8%) | 18 (36.7%) | 3 (37.5%) | |
| Moderate disability | 10 (17.5%) | 7 (14.3%) | 3 (37.5%) | |
| Severe disability | 5 (8.8%) | 4 (8.2%) | 1 (12.5%) | |
| Total FSS score at hospital discharge | 8.0 [8.0,12.0] | 8.0 [8.0,12.0] | 11.0 [9.5,11.5] | 0.0952 |
| Change from baseline to hospital discharge total FSS | 0.0 [-1.0,3.0] | 0.0 [-1.0,2.0] | 2.5 [1.0,4.0] | 0.1402 |
| New morbidity at hospital discharge5 | 16 (28.1%) | 12 (24.5%) | 4 (50.0%) | 0.2021 |
1
Fisher's exact test.
2
Wilcoxon rank-sum test. Continuous variables are summarized using median [Q1, Q3].
3
Ventilation rate and ETCO2 data were available for N=20 total subjects (N=14 surgical cardiac, N=6 medical cardiac).
4
Favorable neurologic outcome defined as discharge PCPC of normal, mild disability, or moderate disability or a discharge PCPC no worse than baseline PCPC.
5
New morbidity defined as an increase of at least 3 between baseline and discharge FSS.