Figure 3.

RBF deficiency induces an inflammatory gene expression profile in rat esophageal tumors. (A) Heat map showing gene expression profiling of the EIN vs. Normal tissues in the R₆N and R₀N groups (n = 2/group). (B) Venn diagram showing the unique and shared differentially-expressed genes between the R₆N and R₀N groups. (C, D) Heat map showing the differential gene expression profiling of EIN vs. Normal tissues in the R₆N (C) and R₀N (D) groups, respectively (n = 2/group). Log₂-fold change ratios are shown in the results. (E, F) Bar diagrams showing the biological processes in the R₆N (E) and R₀N (F) groups. Predicted GO categories ranked by enrichment score [-log₁₀ (P-value)]. Up, Up-regulated expression; Down, Down-regulated expression; 1# and 2#, identifier of rats.