Figure 1.

Patient flow and causes of sustained AKI events. Eighty-two patients (8.1% of the total cohort n=1016) experienced 110 episodes of sustained AKI between them. *The 41 immune checkpoint inhibitor–related sustained AKI events occurred in 30 patients, (3% incidence). **Patient did not have sepsis, nephrotoxin exposure, or a hemodynamic cause, and they did not improve with an intravenous fluid challenge. ICPI, immune checkpoint inhibitor; irAE, immune-related adverse event; MGH, Massachusetts General Hospital; Scr, serum creatinine.