Table 2.
GO analysis of target genes of miR-136-5p Category Term (a) BP, (b) CC and (c) MF
| Category | Term | Count | P Value |
|---|---|---|---|
| GOTERM_BP_DIRECT | GO:0045893~positive regulation of transcription, DNA-templated | 28 | 5.80E-04 |
| GOTERM_BP_DIRECT | GO:0045944~positive regulation of transcription from RNA polymerase II promoter | 44 | 7.55E-04 |
| GOTERM_BP_DIRECT | GO:0030900~forebrain development | 7 | 0.001248761 |
| GOTERM_BP_DIRECT | GO:0000122~negative regulation of transcription from RNA polymerase II promoter | 33 | 0.002861675 |
| GOTERM_BP_DIRECT | GO:0000381~regulation of alternative mRNA splicing, via spliceosome | 6 | 0.00305962 |
| GOTERM_BP_DIRECT | GO:0030509~BMP signaling pathway | 8 | 0.00387334 |
| GOTERM_BP_DIRECT | GO:0061036~positive regulation of cartilage development | 4 | 0.007907442 |
| GOTERM_BP_DIRECT | GO:0043507~positive regulation of JUN kinase activity | 5 | 0.008555415 |
| GOTERM_BP_DIRECT | GO:0007368~determination of left/right symmetry | 6 | 0.014739908 |
| GOTERM_BP_DIRECT | GO:0071805~potassium ion transmembrane transport | 9 | 0.014882492 |
| GOTERM_CC_DIRECT | GO:0030054~cell junction | 22 | 0.007473917 |
| GOTERM_CC_DIRECT | GO:0016324~apical plasma membrane | 16 | 0.008063623 |
| GOTERM_CC_DIRECT | GO:0030027~lamellipodium | 11 | 0.008085509 |
| GOTERM_CC_DIRECT | GO:0005794~Golgi apparatus | 35 | 0.008211005 |
| GOTERM_CC_DIRECT | GO:0030017~sarcomere | 5 | 0.017008275 |
| GOTERM_CC_DIRECT | GO:0005634~nucleus | 160 | 0.019236079 |
| GOTERM_CC_DIRECT | GO:0030864~cortical actin cytoskeleton | 5 | 0.023578095 |
| GOTERM_CC_DIRECT | GO:0005654~nucleoplasm | 88 | 0.024092939 |
| GOTERM_CC_DIRECT | GO:0031512~motile primary cilium | 3 | 0.025527525 |
| GOTERM_CC_DIRECT | GO:0008021~synaptic vesicle | 7 | 0.030297585 |
| GOTERM_MF_DIRECT | GO:0061630~ubiquitin protein ligase activity | 15 | 6.24E-04 |
| GOTERM_MF_DIRECT | GO:0004872~receptor activity | 15 | 0.00254895 |
| GOTERM_MF_DIRECT | GO:0003729~mRNA binding | 10 | 0.007236579 |
| GOTERM_MF_DIRECT | GO:0001077~transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | 14 | 0.012823117 |
| GOTERM_MF_DIRECT | GO:0031433~telethonin binding | 3 | 0.014208887 |
| GOTERM_MF_DIRECT | GO:0043565~sequence-specific DNA binding | 24 | 0.015403247 |
| GOTERM_MF_DIRECT | GO:0004843~thiol-dependent ubiquitin-specific protease activity | 7 | 0.021887456 |
| GOTERM_MF_DIRECT | GO:0043425~bHLH transcription factor binding | 4 | 0.02375109 |
| GOTERM_MF_DIRECT | GO:0000977~RNA polymerase II regulatory region sequence-specific DNA binding | 12 | 0.027343121 |
| GOTERM_MF_DIRECT | GO:0005515~protein binding | 260 | 0.035097746 |