Table 2.
The association of CCNB1 expression level with variables from surgical specimen and TCGA lung adenocarcinoma dataset
| Variable | Univariate | Multivariate | ||||||
|---|---|---|---|---|---|---|---|---|
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| Patient data | TCGA | Patient data | TCGA | |||||
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| OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | |
| Age | 1.010 (0.523-1.946) | 0.977 | 1.284 (0.940-1.754) | 0.116 | - | - | - | - |
| Gender | 3.120 (1.274-7.642) | 0.013 | 2.065 (1.363-3.128) | 0.001 | 3.149 (1.091-9.092) | 0.034 | 2.051 (1.335-3.149) | 0.001 |
| Smoking | 1.708 (1.188-2.454) | 0.004 | 1.177 (1.006-1.377) | 0.043 | 1.648 (1.091-2.486) | 0.017 | 1.185 (1.007-1.395) | 0.041 |
| T stage | 2.418 (1.146-5.103) | 0.021 | 1.498 (1.099-2.041) | 0.010 | 3.374 (1.304-8.729) | 0.012 | 1.475 (1.007-2.162) | 0.046 |
| N stage | 2.259 (1.144-4.460) | 0.019 | 1.502 (1.120-2.016) | 0.007 | 4.869 (1.302-18.212) | 0.019 | 1.659 (1.069-2.573) | 0.024 |
| Metastases | 0.976 (0.059-16.147) | 0.986 | 3.034 (0.855-10.763) | 0.086 | - | - | - | - |
| TNM stage | 1.959 (1.033-3.721) | 0.039 | 1.372 (1.057-1.780) | 0.017 | 0.433 (0.123-1.527) | 0.193 | 0.837 (0.540-1.298) | 0.837 |
Notes: OR: odds ratio; CI, confidence interval; TCGA: The Cancer Genome Atlas.