AS II attenuated oxidative stress damage in DSS-induced UC mice via decreasing the levels of inflammatory factors. The mice were treated with DSS, DSS and 30 mg/kg AS II or DSS plus 50 mg/kg AS II for 0, 2, 4, 6, 8 and 10 day. A-C. The levels of IL-6, TNF-α or IL-β in the colon tissues were measured with ELISA. D-G. The levels of NO, MPO, SOD and MDA in colon tissues were measured with ELISA. **P<0.01 compared with control group; #P<0.05, ##P<0.01 compared with DSS group.