Table 2.
Significantly enriched GO terms and KEGG pathways of DEGs
| Category | Term | Description | Count in gene set | P-value |
|---|---|---|---|---|
| BP term | GO:0030198 | Extracellular matrix organization | 18 | 2.11E-11 |
| BP term | GO:0030199 | Collagen fibril organization | 7 | 2.20E-08 |
| BP term | GO:0043200 | Response to amino acid | 7 | 1.01E-05 |
| BP term | GO:0060840 | Artery development | 6 | 2.51E-05 |
| BP term | GO:0071230 | Cellular response to amino acid stimulus | 5 | 4.92E-05 |
| CC term | GO:0098643 | Banded collagen fibril | 6 | 1.03E-11 |
| CC term | GO:0005583 | Fibrillar collagen trimer | 6 | 1.03E-11 |
| CC term | GO:0098644 | Complex of collagen trimers | 6 | 5.86E-10 |
| CC term | GO:0044420 | Extracellular matrix component | 7 | 2.49E-08 |
| CC term | GO:0031258 | Lamellipodium membrane | 3 | 2.02E-03 |
| MF term | GO:0030020 | Extracellular matrix structural constituent conferring tensile strength | 7 | 2.28E-09 |
| MF term | GO:0005539 | Glycosaminoglycan binding | 13 | 2.09E-08 |
| MF term | GO:0048407 | Platelet-derived growth factor binding | 4 | 2.68E-07 |
| MF term | GO:0008201 | Heparin binding | 10 | 4.31E-07 |
| MF term | GO:0019838 | Growth factor binding | 7 | 4.25E-05 |
| KEGG pathway | hsa04974 | Protein digestion and absorption | 7 | 2.76E-06 |
| KEGG pathway | hsa04512 | ECM-receptor interaction | 6 | 2.14E-05 |
| KEGG pathway | hsa05146 | Amoebiasis | 4 | 4.54E-03 |
| KEGG pathway | hsa04933 | AGE-RAGE signaling pathway in diabetic complications | 4 | 5.25E-03 |
| KEGG pathway | hsa05150 | Staphylococcus aureus infection | 3 | 1.20E-02 |